产品
编 号:F563695
分子式:C8H11Cl2N5
分子量:248.11
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100mg
280
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生物活性:
m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease.

体内研究:
m-CPBG hydrochloride (80 and 160 nM) 显著减少急性盐负荷引起的水摄入量。m-CPBG hydrochloride (third ventricle injection; 160 nM) 显著抑制低血容量动物的水摄入。m-CPBG hydrochloride (third ventricle injection; 320 nM) 减少缺水大鼠的水摄入量。m-CPBG hydrochloride (central administration) 抑制中枢胆碱能和血管紧张素能通路药理学激活诱导的水摄入。Animal Model:Wistar male rats
Dosage:80, 160 and 320 nM
Administration:Ventricle injection
Result:Decreased water intake induced by water deprivation, acute salt load and hypovolemia.
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