产品
编 号：F556960
分子式：C24H28N2O4
分子量：408.49
分子式：C24H28N2O4
分子量：408.49
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
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5mg
询价
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10mg
询价
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25mg
询价
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50mg
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结构图
CAS No: 136152-64-2
产品详情
生物活性：
(R)-(+)-Dimethindene maleate is an orally active H1-receptor blocker with antihistaminic properties in pigs.
体内研究：
(R)-(+)-Dimethindene maleate (10 mL/kg; i.g.; once) shows antihistaminic activity with an ED50 of 2.73 mg/kg in pigs.Animal Model:Male guinea-pigs
Dosage:10 mL/kg
Administration:Oral gavage, once
Result:The ED50-value for a protection from a fatal histamine shock was calculated as 2.73 mg/kg when administered orally 1 h before the injection of histamine. The calculated oral anti-anaphylactic ED50-value was found to be >31.6mg/kg. The oral LD50-values was found to be 988 mg/kg.
体外研究：
(R)-(+)-Dimethindene maleate possesses membrane-stabilising effect.
(R)-(+)-Dimethindene maleate is an orally active H1-receptor blocker with antihistaminic properties in pigs.
体内研究：
(R)-(+)-Dimethindene maleate (10 mL/kg; i.g.; once) shows antihistaminic activity with an ED50 of 2.73 mg/kg in pigs.Animal Model:Male guinea-pigs
Dosage:10 mL/kg
Administration:Oral gavage, once
Result:The ED50-value for a protection from a fatal histamine shock was calculated as 2.73 mg/kg when administered orally 1 h before the injection of histamine. The calculated oral anti-anaphylactic ED50-value was found to be >31.6mg/kg. The oral LD50-values was found to be 988 mg/kg.
体外研究：
(R)-(+)-Dimethindene maleate possesses membrane-stabilising effect.
产品资料
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