产品
编 号：F550635
分子式：C19H22ClFN4O
分子量：376.86
分子式：C19H22ClFN4O
分子量：376.86
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1173239-39-8
产品详情
生物活性：
PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a Ki of 11.6 nM. PF-03463275 has the potential for Schizophrenia research.
体内研究：
PF-03463275 (1-10 mg/kg; s.c.) attenuates oscillatory potentials (OPs).Animal Model:Male Sprague-Dawley rats
Dosage:1, 3 and 10 mg/kg
Administration:S.c.
Result:A dose-dependent reduction in the amplitude of oscillatory potentials (OPs) elicited from the dark-adapted rats.
PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a Ki of 11.6 nM. PF-03463275 has the potential for Schizophrenia research.
体内研究：
PF-03463275 (1-10 mg/kg; s.c.) attenuates oscillatory potentials (OPs).Animal Model:Male Sprague-Dawley rats
Dosage:1, 3 and 10 mg/kg
Administration:S.c.
Result:A dose-dependent reduction in the amplitude of oscillatory potentials (OPs) elicited from the dark-adapted rats.
产品资料
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