产品
编 号：F546684
分子式：C17H22BrNO4
分子量：384.26
分子式：C17H22BrNO4
分子量：384.26
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
询价
询价
结构图
CAS No: 1944-12-3
产品详情
生物活性：
Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research.
体内研究：
Fenoterol hydrobromide (0.7 mg/kg；腹膜内注射；每天两次；持续 3 周) 处理可抑制慢性处理期间的机械异常性疼痛。Animal Model:Male C57BL/6J mice (6 weeks old) with neuropathy
Dosage:0.7 mg/kg
Administration:Intraperitoneal injection; twice a day; for 3 weeks
Result:Alleviated neuropathic allodynia during chronic treatment.
体外研究：
Fenoterol (1 μM；预孵育 30 分钟) 处理可降低 AICAR 诱导的 AMPK 活化、NF-κB 活化和 TNF-α 释放，还显著下调 AMPK 升高的磷酸化水平。 Fenoterol 抑制脂多糖 (LPS) 诱导的 THP-1 细胞中 AMPK 活化和炎性细胞因子的产生。Fenoterol 也是 PC 细胞中有效的外泌体生物发生和/或分泌激活剂。
Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research.
体内研究：
Fenoterol hydrobromide (0.7 mg/kg；腹膜内注射；每天两次；持续 3 周) 处理可抑制慢性处理期间的机械异常性疼痛。Animal Model:Male C57BL/6J mice (6 weeks old) with neuropathy
Dosage:0.7 mg/kg
Administration:Intraperitoneal injection; twice a day; for 3 weeks
Result:Alleviated neuropathic allodynia during chronic treatment.
体外研究：
Fenoterol (1 μM；预孵育 30 分钟) 处理可降低 AICAR 诱导的 AMPK 活化、NF-κB 活化和 TNF-α 释放，还显著下调 AMPK 升高的磷酸化水平。 Fenoterol 抑制脂多糖 (LPS) 诱导的 THP-1 细胞中 AMPK 活化和炎性细胞因子的产生。Fenoterol 也是 PC 细胞中有效的外泌体生物发生和/或分泌激活剂。
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