产品
编 号：F546209
分子式：C11H20N2O6
分子量：276.29
分子式：C11H20N2O6
分子量：276.29
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 997-68-2
产品详情
生物活性：
Saccharopine (L-Saccharopine), a lysine degradation intermediate, is a mitochondrial toxin. Lysine and α-ketoglutarate are converted into Saccharopine by the lysine-ketoglutarate reductase. Saccharopine is then oxidized to α-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine impairs development by disrupting mitochondrial homeostasis.
体内研究：
Saccharopine accumulation induces mitochondrial damage and progressive postnatal growth retardation in Aass mutant mice.
体外研究：
Saccharopine accumulation leads to mitochondrial damage and functional loss which is induced by saccharopine dehydrogenase (SDH) mutations of α-aminoadipate semialdehyde synthase (AASS)-1 in C. elegans.
Saccharopine (L-Saccharopine), a lysine degradation intermediate, is a mitochondrial toxin. Lysine and α-ketoglutarate are converted into Saccharopine by the lysine-ketoglutarate reductase. Saccharopine is then oxidized to α-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine impairs development by disrupting mitochondrial homeostasis.
体内研究：
Saccharopine accumulation induces mitochondrial damage and progressive postnatal growth retardation in Aass mutant mice.
体外研究：
Saccharopine accumulation leads to mitochondrial damage and functional loss which is induced by saccharopine dehydrogenase (SDH) mutations of α-aminoadipate semialdehyde synthase (AASS)-1 in C. elegans.
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