产品
编 号：F545715
分子式：C13H8N2OS
分子量：240.28
分子式：C13H8N2OS
分子量：240.28
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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结构图
CAS No: 99420-15-2
产品详情
生物活性：
BTZO-1 binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro.
体外研究：
BTZO-1 (0-330 nM; 24 hours) dose-dependently suppressed serum deprivation-induced cardiomyocyte death; the minimum effective concentration (MEC1.5),the concentration of a sample necessary to give a 50% increase in cell viability, is 16 nM.BTZO-1 (0.37 μM; 21 hours) upregulates mRNA protein levels of GST Ya and HO-1 in cardiomyocytes.
BTZO-1 binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro.
体外研究：
BTZO-1 (0-330 nM; 24 hours) dose-dependently suppressed serum deprivation-induced cardiomyocyte death; the minimum effective concentration (MEC1.5),the concentration of a sample necessary to give a 50% increase in cell viability, is 16 nM.BTZO-1 (0.37 μM; 21 hours) upregulates mRNA protein levels of GST Ya and HO-1 in cardiomyocytes.
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