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编 号：F545499
分子式：C87H148N26O24
分子量：1942.27
分子式：C87H148N26O24
分子量：1942.27
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CAS No: 99273-04-8
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生物活性：
CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions.
体内研究：
CKS-17 (10 μM; i.d.; B6AF1 mice and C57BL/6J mice) inhibits delayed-type hypersensitivity (DTH) reactions to sheep erythrocytes in the feet of mice.Animal Model:B6AF1 mice and C57BL/6J mice with DTH models
Dosage:10 μM
Administration:Intradermal injection, into the right hind footpad
Result:Had a transient depressive effect on DTH reaction.
体外研究：
CKS-17 (THP-1 cells) induces increased intracellular cAMP via activation of adenylate cyclase.CKS-17 (15 μM; EL4 cells) inhibits interleukin-2 production by tumor cell products.
CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions.
体内研究：
CKS-17 (10 μM; i.d.; B6AF1 mice and C57BL/6J mice) inhibits delayed-type hypersensitivity (DTH) reactions to sheep erythrocytes in the feet of mice.Animal Model:B6AF1 mice and C57BL/6J mice with DTH models
Dosage:10 μM
Administration:Intradermal injection, into the right hind footpad
Result:Had a transient depressive effect on DTH reaction.
体外研究：
CKS-17 (THP-1 cells) induces increased intracellular cAMP via activation of adenylate cyclase.CKS-17 (15 μM; EL4 cells) inhibits interleukin-2 production by tumor cell products.
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