产品
编 号：F545162
分子式：C86H131N25O27
分子量：1947.12
分子式：C86H131N25O27
分子量：1947.12
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CAS No: 99027-06-2
产品详情
生物活性：
C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells.
体外研究：
C3 Peptide P16 (7.4 μM; 18 h) triggers in vitro and in vivo phosphorylations and in vitro proliferation of human B lymphocytes, depending on the stage of cell differentiation. C3 Peptide P16 (7 nM; 60 min; 4 ℃) induces in vivo tyrosine phosphorylation of pp105 and (15 μM; 6-8 d) enhances proliferation only of CR2-pos. but not of CR2-neg. cell lines in vitro.C3 Peptide P16 (7.4 μM; 18 h) also induces in vivo tyrosine phosphorylation of pp100 and in vivo proliferation of only small dense resting B lymphocytes and not other B lymphocyte subpopulations nor T lymphocytes. C3 Peptide P16 (0.3-10 μM; 3 min; 33 ℃) dose-dependently regulates pp105 phosphorylation, as well as C3d fragment present in trypsin-cleaved C3.
C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells.
体外研究：
C3 Peptide P16 (7.4 μM; 18 h) triggers in vitro and in vivo phosphorylations and in vitro proliferation of human B lymphocytes, depending on the stage of cell differentiation. C3 Peptide P16 (7 nM; 60 min; 4 ℃) induces in vivo tyrosine phosphorylation of pp105 and (15 μM; 6-8 d) enhances proliferation only of CR2-pos. but not of CR2-neg. cell lines in vitro.C3 Peptide P16 (7.4 μM; 18 h) also induces in vivo tyrosine phosphorylation of pp100 and in vivo proliferation of only small dense resting B lymphocytes and not other B lymphocyte subpopulations nor T lymphocytes. C3 Peptide P16 (0.3-10 μM; 3 min; 33 ℃) dose-dependently regulates pp105 phosphorylation, as well as C3d fragment present in trypsin-cleaved C3.
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