产品
编 号：F006296
分子式：C14H24ClN3O3S
分子量：349.88
分子式：C14H24ClN3O3S
分子量：349.88
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 101526-62-9
产品详情
生物活性：
Sematilide hydrochloride (CK-1752 hydrochloride) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent.
体内研究：
Sematilide (0.3-1.0 mg/kg, intravenously i.v.) is effective in a canine model of arrhythmia.Animal Model:Mongrel dogs of either sex (10-18 kg body weight)
Dosage:0.3, 1, 3, and 10 mg/kg
Administration:I.v. infusions
Result:Demonstrated antiarrhythmic effects at 0.3 and 3.0 mg/kg.
体外研究：
Application of 10, 30, 100 and 300 μM Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM).
Sematilide hydrochloride (CK-1752 hydrochloride) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent.
体内研究：
Sematilide (0.3-1.0 mg/kg, intravenously i.v.) is effective in a canine model of arrhythmia.Animal Model:Mongrel dogs of either sex (10-18 kg body weight)
Dosage:0.3, 1, 3, and 10 mg/kg
Administration:I.v. infusions
Result:Demonstrated antiarrhythmic effects at 0.3 and 3.0 mg/kg.
体外研究：
Application of 10, 30, 100 and 300 μM Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM).
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备