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编 号:F544482
分子式:C21H21N2NaO5S
分子量:436.46
产品类型
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CAS No: 985-16-0
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生物活性:
Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections.
体内研究:
Nafcillin sodium (100 mg/kg; s.c.) exhibits bactericidal activity against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA), with MICs of 0.5 μg/mL and 64.0 μg/mL for S. aureus strains Xen-29 and Xen-1, respectively, in mice.Animal Model:CD-1 female mice (20-25 g), with MRSA- and MSSA-infected
Dosage:100 mg/kg
Administration:Subcutaneous injection
Result:Protected 100% of the healthy mice with MSSA infections.