产品
编 号:F544098
分子式:C16H12O3S
分子量:284.33
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是否有货
10mM*1mL in DMSO
2150
In-stock
5mg
1950
In-stock
10mg
3150
In-stock
25mg
6750
In-stock
50mg
10800
In-stock
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生物活性:
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).

体外研究:
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed.
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