产品
编 号：F541105
分子式：C24H27NO5S
分子量：441.54
分子式：C24H27NO5S
分子量：441.54
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CAS No: 96389-69-4
产品详情
生物活性：
Crisnatol (BWA770U) mesylate is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol mesylate shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts.
体内研究：
Crisnatol (25 mg/kg; p.o.; single dose) mesylate 显示出口服活性，并通过放射自显影显示大鼠粪便提取物的稳定代谢物谱。
体外研究：
Crisnatol (1.3 μg/mL; 24-72 h) mesylate 抑制 HepG2 细胞的复制，使细胞活力降低 35%。
Crisnatol (BWA770U) mesylate is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol mesylate shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts.
体内研究：
Crisnatol (25 mg/kg; p.o.; single dose) mesylate 显示出口服活性，并通过放射自显影显示大鼠粪便提取物的稳定代谢物谱。
体外研究：
Crisnatol (1.3 μg/mL; 24-72 h) mesylate 抑制 HepG2 细胞的复制，使细胞活力降低 35%。
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