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编 号:F539744
分子式:C22H27FN4O2
分子量:398.47
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. 18FDPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model.

体内研究:
[18F]DPA-714 binding significantly increases in vivo as a result of AD‐like pathology and age in APPswe×PS1Δe9 mice.
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