产品
编 号:F539560
分子式:C14H16ClN5O2S
分子量:353.83
产品类型
结构图
CAS No: 957485-64-2
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产品详情
生物活性:
FPH2 induces of functional proliferation of primary human hepatocytes and may lead to the development of new therapeutics for liver diseases.
体外研究:
FPH2 induces functional proliferation of hepatocytes in vitro, and thus may be useful for expanding mature human primary hepatocytes. FPH1 and FPH2 can increase in hepatocyte nuclei count and/or elevate the number of nuclei undergoing mitosis during primary screening, and these effects on hepatocytes are concentration dependent. Cells treated with FPH1 and FPH2 also maintain their liver-specific functions. Over 7 days, FPH2 induces hepatocyte doublings at a rate that is consistent with reported liver regeneration kinetics in vivo.