产品
编 号：F538625
分子式：C24H33N3O4
分子量：427.54
分子式：C24H33N3O4
分子量：427.54
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
708
In-stock
200mg
1080
In-stock
500mg
1760
In-stock
结构图
CAS No: 95635-55-5
产品详情
生物活性：
Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. Antianginal agent.
体内研究：
Ranolazine (Bolus injection 10 mg/kg and infusion 9.6 mg/kg/h; bolus injection; for 145 minutes; male Wistar rats) treatment significantly reduces infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion.Animal Model:Male Wistar rats (240-350 g)
Dosage:Bolus injection 10 mg/kg and infusion (9.6 mg/kg/h)
Administration:Bolus injection; for 145 minutes
Result:Significantly reduced infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion.
Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. Antianginal agent.
体内研究：
Ranolazine (Bolus injection 10 mg/kg and infusion 9.6 mg/kg/h; bolus injection; for 145 minutes; male Wistar rats) treatment significantly reduces infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion.Animal Model:Male Wistar rats (240-350 g)
Dosage:Bolus injection 10 mg/kg and infusion (9.6 mg/kg/h)
Administration:Bolus injection; for 145 minutes
Result:Significantly reduced infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion.
产品资料
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