产品
编 号：F538368
分子式：C27H31FN6OS
分子量：506.64
分子式：C27H31FN6OS
分子量：506.64
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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2mg
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 955977-50-1
产品详情
生物活性：
PI-3065 is a potent inhibitor of PI3K p110δ, with IC50 and Ki values of 5 nM and 1.5 nM, and exhibits less potent activity against p110α, p110β, p110γ with IC50s of 910, 600, >10000 nM.
体内研究：
PI-3065 (75 mg/kg, p.o.) inhibits the growth of 4T1 tumours in the BALB/c mice without obvious body weight loss.
体外研究：
PI-3065 exhibits no inhibition of the growth of 4T1 cells, which do not express detectable levels of p110δ.
PI-3065 is a potent inhibitor of PI3K p110δ, with IC50 and Ki values of 5 nM and 1.5 nM, and exhibits less potent activity against p110α, p110β, p110γ with IC50s of 910, 600, >10000 nM.
体内研究：
PI-3065 (75 mg/kg, p.o.) inhibits the growth of 4T1 tumours in the BALB/c mice without obvious body weight loss.
体外研究：
PI-3065 exhibits no inhibition of the growth of 4T1 cells, which do not express detectable levels of p110δ.
产品资料
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