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编 号：F535459
分子式：C12H14N2O2
分子量：218.25
分子式：C12H14N2O2
分子量：218.25
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CAS No: 949925-07-9
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生物活性：
(R)-Phenylpiracetam (MRZ 9547) is a dopamine transporter (DAT) inhibitor (Ki: 14.8 μM; IC50: 65.5 μM). (R)-Phenylpiracetam can be used for the research of the neurological or neuropsychiatric disorders.
体内研究：
(R)-Phenylpiracetam (50 mg/kg; p.o. or i.p.; single-dose) reaches the mouse brain tissue 15 min after administration.(R)-Phenylpiracetam (10, 25, 50mg/kg; p.o.; pretreatment for 7 days) dose-dependently reduces paw oedema and the antinociceptive response on carrageenan induced mouse.
体外研究：
(R)-Phenylpiracetam displaces the binding of [125I] RTI-55 (IC50 = 4.82 μM) to human recombinant DAT expressed in CHO-K1 cells.
(R)-Phenylpiracetam (MRZ 9547) is a dopamine transporter (DAT) inhibitor (Ki: 14.8 μM; IC50: 65.5 μM). (R)-Phenylpiracetam can be used for the research of the neurological or neuropsychiatric disorders.
体内研究：
(R)-Phenylpiracetam (50 mg/kg; p.o. or i.p.; single-dose) reaches the mouse brain tissue 15 min after administration.(R)-Phenylpiracetam (10, 25, 50mg/kg; p.o.; pretreatment for 7 days) dose-dependently reduces paw oedema and the antinociceptive response on carrageenan induced mouse.
体外研究：
(R)-Phenylpiracetam displaces the binding of [125I] RTI-55 (IC50 = 4.82 μM) to human recombinant DAT expressed in CHO-K1 cells.
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