产品
编 号:F534738
分子式:C8H6Cl2O3
分子量:221.04
产品类型
结构图
CAS No: 94-75-7
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产品详情
生物活性:
2,4-D (2, 4-dichlorophenoxyacetic acid) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D can induce apoptosis. 2,4-D inhibits DNA and protein synthesis, thereby preventing normal plant growth and development.
体内研究:
2,4-D (100 或 200 mg/kg, 灌胃, 连续30 天) 对雄性大鼠生殖系统有毒性作用。Animal Model:Adult Wistar male rats
Dosage:100 or 200 mg/kg
Administration:i.g.
Result:Decreased the testis, seminal vesicles and prostate relative weight.Decreased the number of spermatozoa and sperm motility.Increased the level of FSH and LH.
体外研究:
2,4-D (25-200 μM, 72 h) 抑制 A549 和 WI38 的细胞活力,IC50 值分别为 126 ± 2.25 μM 和 115 ± 4.39 μM。通过影响细胞周期,诱导细胞凋亡。