产品
编 号：F533895
分子式：C7H9IN2O
分子量：264.06
分子式：C7H9IN2O
分子量：264.06
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
25mg
100
In-stock
100mg
200
In-stock
250mg
320
In-stock
结构图
CAS No: 94-63-3
产品详情
生物活性：
Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning.
体内研究：
Pralidoxime iodide (10-150 mg/kg; intramuscular administration, once) reverses paraoxon-induced respiratory toxicity in mice.Animal Model:Male F1B6D2 mice (toxic but non-lethal model of diethylparaoxon in awake, unrestrained mice)
Dosage:10, 50, 100 and 150 mg/kg
Administration:Intramuscularly, once
Result:Induced a partial, albeit complete, reversal of respiratory toxicity at 50 mg/kg, and completely reversed diethylparaoxon-induced respiratory toxicity in mice at 150 mg/kg.
Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning.
体内研究：
Pralidoxime iodide (10-150 mg/kg; intramuscular administration, once) reverses paraoxon-induced respiratory toxicity in mice.Animal Model:Male F1B6D2 mice (toxic but non-lethal model of diethylparaoxon in awake, unrestrained mice)
Dosage:10, 50, 100 and 150 mg/kg
Administration:Intramuscularly, once
Result:Induced a partial, albeit complete, reversal of respiratory toxicity at 50 mg/kg, and completely reversed diethylparaoxon-induced respiratory toxicity in mice at 150 mg/kg.
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