产品
编 号：F532968
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规格
价格
是否有货
1mg
询价
询价
5mg
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询价
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CAS No: 944548-37-2
产品详情
生物活性：
Rafivirumab (CR57) is an anti-rabies virus monoclonal antibody for the prophylaxis of rabies. Rafivirumab has neutralizing potency against a broad spectrum of RABV variants. Rafivirumab can be used for research of cocktails.
体内研究：
Rafivirumab (3-12 μg/kg，肌肉注射) 与 CR4098 一起提高了感染蝙蝠狂犬病病毒的叙利亚仓鼠的存活率。Animal Model:Syrian hamsters infected with bat rabies viruses.
Dosage:6, 12, 16, 18 or 24 μg/kg of CL184 (mixture of Rafivirumab and CR4098 in 1:1 protein ratio)
Administration:i.m.
Result:Increased survival rate.
体外研究：
Rafivirumab 显示出对一系列 RABV 分离株的中和作用。Rafivirumab 与 RABV 糖蛋白的抗原位点 I 结合。Rafivirumab 完全中和野生型 ERA439 和 N336D R346K，EC50 范围在 3 到 5 pg/mL 之间。
Rafivirumab (CR57) is an anti-rabies virus monoclonal antibody for the prophylaxis of rabies. Rafivirumab has neutralizing potency against a broad spectrum of RABV variants. Rafivirumab can be used for research of cocktails.
体内研究：
Rafivirumab (3-12 μg/kg，肌肉注射) 与 CR4098 一起提高了感染蝙蝠狂犬病病毒的叙利亚仓鼠的存活率。Animal Model:Syrian hamsters infected with bat rabies viruses.
Dosage:6, 12, 16, 18 or 24 μg/kg of CL184 (mixture of Rafivirumab and CR4098 in 1:1 protein ratio)
Administration:i.m.
Result:Increased survival rate.
体外研究：
Rafivirumab 显示出对一系列 RABV 分离株的中和作用。Rafivirumab 与 RABV 糖蛋白的抗原位点 I 结合。Rafivirumab 完全中和野生型 ERA439 和 N336D R346K，EC50 范围在 3 到 5 pg/mL 之间。
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