产品
编 号：F532769
分子式：C25H26ClFN4O4
分子量：500.95
分子式：C25H26ClFN4O4
分子量：500.95
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
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5mg
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10mg
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结构图
CAS No: 944258-89-3
产品详情
生物活性：
Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19.9 nM. Antineoplastic activities.
体内研究：
Simotinib has been shown to exert its antitumor activity by inhibiting EGFR phosphorylation in nude xenograft model.
体外研究：
Simotinib inhibits in a dose-dependent manner EGFR and the growth of human A431 tumor cells with high expression of EGFR, with no significant activity on other investigated kinases.
Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19.9 nM. Antineoplastic activities.
体内研究：
Simotinib has been shown to exert its antitumor activity by inhibiting EGFR phosphorylation in nude xenograft model.
体外研究：
Simotinib inhibits in a dose-dependent manner EGFR and the growth of human A431 tumor cells with high expression of EGFR, with no significant activity on other investigated kinases.
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