产品
编 号:F529892
分子式:C35H46O19
分子量:770.73
产品类型
结构图
CAS No: 94079-81-9
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产品详情
生物活性:
Poliumoside, a caffeoylated phenylpropanoid glycoside, is isolated from Brandisia hancei stems and leaves. Poliumoside is an advanced glycation end product (AGE) formation and rat lens aldose reductase (RLAR) inhibitor, with IC50s of 19.69 and 8.47 μM, respectively. Poliumoside also has antiinflammatory and antioxidant activity.
体内研究:
Poliumoside inhibits vessel dilation in larval zebrafish.
体外研究:
Poliumoside inhibits AGE formation and RLAR, with IC50s of 19.69, and 8.47 μM, respectively.Poliumoside (5-30 μM; 3 h) inhibits AAPH-induced hemolysis of rat red blood cells in vitro.Poliumoside (12.5-100 μM; pretreated 2 h) inhibits the release of TNF-α and IL-6 in LPS-induced RAW 264.7?cells.