产品
编 号：F526950
分子式：C9H4Br4O2
分子量：463.74
分子式：C9H4Br4O2
分子量：463.74
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 934358-00-6
产品详情
生物活性：
TBCA is a highly selective CK2 (casein kinase II) inhibitor with an IC50 of 110 nM and a Ki of 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases.
体外研究：
TBCA (0-100 μM; 24 hours) shows a drastic effect on Jurkat cells viability.TBCA also inhibits CK2 double mutant (Val66 Ile174) with an IC50 of 0.68 μM.TBCA dose-dependently inhibits platelet aggregation and secretion induced by various agonists including 2-MeSADP, AYPGKF, SFLLRN, and CRP. TBCA also inhibits phosphorylation of PDK1, Akt, and GSK3β induced by AYPGKF.
TBCA is a highly selective CK2 (casein kinase II) inhibitor with an IC50 of 110 nM and a Ki of 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases.
体外研究：
TBCA (0-100 μM; 24 hours) shows a drastic effect on Jurkat cells viability.TBCA also inhibits CK2 double mutant (Val66 Ile174) with an IC50 of 0.68 μM.TBCA dose-dependently inhibits platelet aggregation and secretion induced by various agonists including 2-MeSADP, AYPGKF, SFLLRN, and CRP. TBCA also inhibits phosphorylation of PDK1, Akt, and GSK3β induced by AYPGKF.
产品资料
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