产品
编 号：F525944
分子式：C12H14O3
分子量：206.24
分子式：C12H14O3
分子量：206.24
产品类型
规格
价格
是否有货
500mg
100
In-stock
1g
120
In-stock
结构图
CAS No: 93-28-7
产品详情
生物活性：
Eugenol acetate (Eugenyl acetate) is an antibacterial, anticancer, anti-inflammatory and antioxidant. Eugenol acetate inhibits NF-κB and enhances the expression of p53 and p21 (WAF1). Eugenol acetate can prevent chemically induced skin cancer, inhibit cancer cell proliferation and induce apoptosis.
体内研究：
Eugenol acetate (15% v/v, 共 30 μL; 每周 2 次, 共 28 周) 引起小鼠皮肤的 p53 和 p21WAF1 表达增加，和癌组织中细胞凋亡。Eugenol acetate (3-300 mg/kg; 口服或腹腔注射, 单剂量) 可发挥镇痛作用，抑制乙酸、谷氨酸盐、红藻氨酸引起的不同的小鼠急性疼痛模型。Animal Model:Acute pain model in mice
Dosage:3-300 mg/kg
Administration:Oral (p.o.) or i.p. routes 60 or 30 min before the acetic acid injection, respectively.
Result:Produced a marked and dose-related inhibition of acetic acid-induced abdominal constrictions in mice, with mean ID50 values (and their 95% confidence limits) of 51.3 (23.5-111.9) and 50.2 (38.4-65.6) mg/kg and inhibitions of 82 ± 10% and 90 ± 6% for the p.o. and i.p. treatments, respectively.
Eugenol acetate (Eugenyl acetate) is an antibacterial, anticancer, anti-inflammatory and antioxidant. Eugenol acetate inhibits NF-κB and enhances the expression of p53 and p21 (WAF1). Eugenol acetate can prevent chemically induced skin cancer, inhibit cancer cell proliferation and induce apoptosis.
体内研究：
Eugenol acetate (15% v/v, 共 30 μL; 每周 2 次, 共 28 周) 引起小鼠皮肤的 p53 和 p21WAF1 表达增加，和癌组织中细胞凋亡。Eugenol acetate (3-300 mg/kg; 口服或腹腔注射, 单剂量) 可发挥镇痛作用，抑制乙酸、谷氨酸盐、红藻氨酸引起的不同的小鼠急性疼痛模型。Animal Model:Acute pain model in mice
Dosage:3-300 mg/kg
Administration:Oral (p.o.) or i.p. routes 60 or 30 min before the acetic acid injection, respectively.
Result:Produced a marked and dose-related inhibition of acetic acid-induced abdominal constrictions in mice, with mean ID50 values (and their 95% confidence limits) of 51.3 (23.5-111.9) and 50.2 (38.4-65.6) mg/kg and inhibitions of 82 ± 10% and 90 ± 6% for the p.o. and i.p. treatments, respectively.
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