产品
编 号：F525561
分子式：C17H17FN2O5
分子量：348.33
分子式：C17H17FN2O5
分子量：348.33
产品类型
规格
价格
是否有货
5mg
询价
询价
结构图
CAS No: 931399-19-8
产品详情
生物活性：
GSK360A is a potent and orally active HIF-PHD inhibitor with IC50 values of 10, 100, and 126 nM for PHD1, PHD2, and PHD3, respectively. GSK360A activates the HIF-1 alpha pathway and protect the failing heart after myocardial infarction (MI) .
体内研究：
GSK360A (30 mg/kg i.g.) 在已建立的心室功能障碍模型中改善长期心室功能、重塑和血管分布。Animal Model:male Lewis rats with ventricular dysfunction model
Dosage:30 mg/kg
Administration:oral gavage
Result:Increased circulating levels of erythropoietin and hemoglobin and hemoxygenase-1 expression in the heart and skeletal muscle of male rats.
GSK360A is a potent and orally active HIF-PHD inhibitor with IC50 values of 10, 100, and 126 nM for PHD1, PHD2, and PHD3, respectively. GSK360A activates the HIF-1 alpha pathway and protect the failing heart after myocardial infarction (MI) .
体内研究：
GSK360A (30 mg/kg i.g.) 在已建立的心室功能障碍模型中改善长期心室功能、重塑和血管分布。Animal Model:male Lewis rats with ventricular dysfunction model
Dosage:30 mg/kg
Administration:oral gavage
Result:Increased circulating levels of erythropoietin and hemoglobin and hemoxygenase-1 expression in the heart and skeletal muscle of male rats.
产品资料
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