产品
编 号:F524779
分子式:C8H12N2O2
分子量:168.19
产品类型
结构图
CAS No: 92933-48-7
联系客服
产品详情
生物活性:
LUF6283 is a potent and orally active HCA(2) partial agonist, with a Ki of 0.55 μM. LUF6283 can achieve the beneficial lipid lowering effect of niacin without producing the unwanted cutaneous flushing side effect.
体内研究:
LUF6283 (C57BL/6 mice, 400 mg/kg, Oral gavage, once a day for 4 weeks) has no effect on adipose tissue ATGL/HSL expression, and significantly reduces the expression of apolipoprotein B (APOB).