产品
编 号：F061182
分子式：C20H16N6
分子量：340.38
分子式：C20H16N6
分子量：340.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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50mg
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结构图
CAS No: 1185763-69-2
产品详情
生物活性：
NVP-BVU972 is an selective and potent Met inhibitor, with an IC50 of 14 nM. NVP-BVU972 also exhibits good anti-proliferative activity against Met with drug-resistant mutations and inhibits phosphorylation. NVP-BVU972 can be used in study of cancer.
体外研究：
NVP-BVU972 (600 nM-9.6 μM; 72 h) shows good antiproliferative activity to BaF3 cells with MET mutations.NVP-BVU972 (0-10 μM; 2 h) reduces TPR-MET phosphorylation in a dose-dependent manner in BaF3 TPR-MET cells.
NVP-BVU972 is an selective and potent Met inhibitor, with an IC50 of 14 nM. NVP-BVU972 also exhibits good anti-proliferative activity against Met with drug-resistant mutations and inhibits phosphorylation. NVP-BVU972 can be used in study of cancer.
体外研究：
NVP-BVU972 (600 nM-9.6 μM; 72 h) shows good antiproliferative activity to BaF3 cells with MET mutations.NVP-BVU972 (0-10 μM; 2 h) reduces TPR-MET phosphorylation in a dose-dependent manner in BaF3 TPR-MET cells.
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