产品
编 号:F524013
分子式:C28H34O8S2
分子量:562.69
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
Ecamsule is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression. Ecamsule has the potential for the research of polymorphous light eruption (PMLE) .

体外研究:
Ecamsule is a broad-spectrum UVA-absorber with maximum absorbance at 344 nm.Wild-type Fibs E6/E7 cells are more sensitive towards Ecamsule (200-1600 μM) treatment.. Ecamsule counteractes UV and AAPH induced ROS-formation..The effects are dose-dependent, reaching a maxi-mum ROS reduction by 25.7% at the highest tested concentration of 1600 μM in the UV-setting. With the same concentration of Ecamsule, oxidative stress that had been trigged by AAPH is reduced by 10.8% and basal levels are attenuated by 16.9%.. Ecamsule increases the viability at the highest applied concentration of 1600 μM in the AAPH-treated cells.
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