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编 号:F522832
分子式:C20H26Cl2N2O
分子量:381.34
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生物活性:
10-DEBC hydrochloride is a selective Akt inhibitor, with an IC50 of 1.28 μM. 10-DEBC hydrochloride is a novel anti-TB compound.

体外研究:
10-DEBC is found to inhibit the growth of Mtb in whole-cell assay with an IC50 of 12.8 μM, while inhibiting replication of Mtb inside iMACs with an IC50 of 1.5 μM, without host cell toxicity even at the highest concentration of 25 μM.
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