产品
编 号:F522537
分子式:C10H8O2
分子量:160.17
产品类型
结构图
CAS No: 92-48-8
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产品详情
生物活性:
6-Methylcoumarin is a synthetic fragrance widely used in cosmetics.
体外研究:
6-Methylcoumarin is reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models. HaCaT cells are treated with 6-Methylcoumarin (1-105 nM) and/or UVA (5 J cm-2), and γ-H2AX is detected by immunofluorescence staining and western blotting 4hours after the treatments. 6-Methylcoumarin clearly produces γ-H2AX-positive cells under UVA irradiation from a concentration of 100 nM.