产品
编 号:F522295
分子式:C15H9N5O
分子量:275.26
产品类型
结构图
CAS No: 924296-19-5
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产品详情
生物活性:
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8.
体外研究:
DUBs-IN-2 (compound 22 e) is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5?μM.