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编 号:F522295
分子式:C15H9N5O
分子量:275.26
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10mM*1mL in DMSO
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2mg
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5mg
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10mg
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生物活性:
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8.

体外研究:
DUBs-IN-2 (compound 22 e) is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5?μM.
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