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编 号:F522294
分子式:C20H11N5O
分子量:337.33
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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生物活性:
DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs), with an IC50 of 0.85 μM for USP8.

体外研究:
DUBs-IN-1 (22 d) is an active inhibitor of ubiquitin-specific proteases, with an IC50 of 0.85 μM for USP8. DUBs-IN-1 is inactive toward USP7 (IC50, >100 μM). DUBs-IN-1 and its analogs reduce the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC50s ranging from 0.5 μM to 1.5?μM.
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