产品
编 号：F521477
分子式：C11H9ClN4O2
分子量：264.67
分子式：C11H9ClN4O2
分子量：264.67
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 92285-87-5
产品详情
生物活性：
L82-G17 is an uncompetitive DNA ligase I (Lig I)-selective inhibitor. L82-G17 inhibits the third step of the ligation reaction, phosphodiester bond formation. L82-G17can be used as a probe of the catalytic activity.
体外研究：
L82-G17 (200 μM, 30 min) has selective uncompetitive inhibitory effect for LigI. L82-G17 (0-100 μM) increases LigI binding to non-ligatable nicked DNA binding.L82-G17 inhibits step 3 of the ligation reaction, phosphodiester bond formation.L82-G17 (0-100 μM) inhibits DNA synthesis, cell viability and s induces DNA damage.
L82-G17 is an uncompetitive DNA ligase I (Lig I)-selective inhibitor. L82-G17 inhibits the third step of the ligation reaction, phosphodiester bond formation. L82-G17can be used as a probe of the catalytic activity.
体外研究：
L82-G17 (200 μM, 30 min) has selective uncompetitive inhibitory effect for LigI. L82-G17 (0-100 μM) increases LigI binding to non-ligatable nicked DNA binding.L82-G17 inhibits step 3 of the ligation reaction, phosphodiester bond formation.L82-G17 (0-100 μM) inhibits DNA synthesis, cell viability and s induces DNA damage.
产品资料
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