生物活性: Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.
体外研究: Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin.