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编 号：F520490
分子式：C127H205N45O39S3
分子量：3080.46
分子式：C127H205N45O39S3
分子量：3080.46
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CAS No: 91917-63-4
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生物活性：
Atrial natriuretic factor (1-28) (human, porcine) is a potent suppressor of pro-opiomelanocortin (POMC) mRNA but a weak inhibitor of βEP-LI release.
体内研究：
ANF-(1-28) (0.5 μg/kg/min) infusion attenuates the rise in plasma creatinine levels by approximately 50% on each day of the study.
体外研究：
ANF-(1-28) markedly increaseS guanosine 3',5'-cyclic monophosphate (cGMP) from 1.3 +/- 0.3 to 106 +/- 22 pmol cGMP/10(6) cells [50% effective dosage (ED50) = 1.2 nM].
Atrial natriuretic factor (1-28) (human, porcine) is a potent suppressor of pro-opiomelanocortin (POMC) mRNA but a weak inhibitor of βEP-LI release.
体内研究：
ANF-(1-28) (0.5 μg/kg/min) infusion attenuates the rise in plasma creatinine levels by approximately 50% on each day of the study.
体外研究：
ANF-(1-28) markedly increaseS guanosine 3',5'-cyclic monophosphate (cGMP) from 1.3 +/- 0.3 to 106 +/- 22 pmol cGMP/10(6) cells [50% effective dosage (ED50) = 1.2 nM].
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