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编 号:F060112
分子式:C23H29NO5
分子量:399.48
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
Tesmilifene fumarate (DPPE fumarate), an H1C receptor antagonist, potentiates a wide range of cytotoxics and even to offer some protection of normal cells.

体内研究:
Tesmilifene (DPPE, 20 mg/kg (s.c.) and 20 μg (icv in 5 μL)) potentiated seizures induced by both convulsants.Animal Model:Male BKTO mice (25-45 g).
Dosage:20 mg/kg (s.c.) and 20 μg (icv in 5 μL).
Administration:S.C. and icv.
Result:Potentiated seizures induced by both convulsants.

体外研究:
Tesmilifene may modulate the effects of 12(S)HETE in cancer cells, and indirectly, influence the susceptibility of cellular DNA to chemotherapy.
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