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编 号：F519598
分子式：C22H32O5
分子量：376.49
分子式：C22H32O5
分子量：376.49
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CAS No: 916888-47-6
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生物活性：
Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation.
体内研究：
Resolvin D3 (RvD3; 100 ng/100 μl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis.Animal Model:Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice
Dosage:100 ng/100 μl
Administration:IP; daily for 6 days
Result:Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis.
体外研究：
RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells.
Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation.
体内研究：
Resolvin D3 (RvD3; 100 ng/100 μl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis.Animal Model:Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice
Dosage:100 ng/100 μl
Administration:IP; daily for 6 days
Result:Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis.
体外研究：
RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells.
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