产品
编 号:F517730
分子式:C20H15N3O6
分子量:393.35
产品类型
结构图
CAS No: 91421-42-0
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产品详情
生物活性:
Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells.
体外研究:
Rubitecan (RFS 2000) inhibits U-CH1, U-CH2, and CCL4 cells with IC50s 0.32, 0.83, and 7.7 μM, respectively.