产品
编 号:F517286
分子式:C31H25F3N2O4
分子量:546.54
产品类型
结构图
CAS No: 913541-47-6
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产品详情
生物活性:
SLX-4090 is an orally active enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. SLX-4090 can be used for the research of dyslipidemia.
体内研究:
SLX-4090 (orally, 30 mg/kg) reduces postprandial lipids by 50% with an ED50 value 7 mg/kg in rats.
体外研究:
SLX-4090 inhibits apolipoprotein B (IC50 value 9.6 nM) but not apolipoprotein A1 secretion in Caco-2 cells.