产品
编 号:F515736
分子式:C20H22ClN7OS
分子量:443.95
产品类型
结构图
CAS No: 910297-51-7
联系客服
产品详情
生物活性:
N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, Dasatinib is a multi-kinase inhibitor that potently inhibits Bcr-Abl, Src family and platelet-derived growth factor receptor kinases. N-Deshydroxyethyl Dasatinib can be used in cancer and immune disease research.
体内研究:
1.19Pharmacokinetic Parameters of N-Deshydroxyethyl Dasatinib in Wistar Rats. AnalyteCmax (ng/mL)AUC0-t (h*ng/mL) AUC0-inf (h*ng/mL) Tmax (h) T1/2 (h) Kel (h-1)
N-Deshydroxyethyl Dasatinib2.058.7 23.9 2.0 10.293 0.072