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编 号:F513022
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CAS No: 9039-53-6
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生物活性:
Urokinase (peptidolytic) (EC 3.4.21.73) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research.
体外研究:
Urokinase peptidolytic(uPA) can increase the expression of uPAR protein and mRNA levels in non-small cell lung cancer (NSCLC).