产品
编 号：F511683
分子式：C22H26N4O3
分子量：394.47
分子式：C22H26N4O3
分子量：394.47
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
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询价
结构图
CAS No: 901245-65-6
产品详情
生物活性：
GSK-5959 is a potent, selective and cell permeable BRPF1 bromodomain inhibitor with an IC50 of ~ 80 nM.
体外研究：
GSK-5959 (3a) also displays selectivity over the closely related family members, BRPF2 (100-fold) and BRPF3 (>1000-fold).GSK-5959 (3a) exhibits an EC50 = 0.98 μM) in cellular NanoBRET assay.GSK-5959 has no effect on TRIM24 SUMOylation.
GSK-5959 is a potent, selective and cell permeable BRPF1 bromodomain inhibitor with an IC50 of ~ 80 nM.
体外研究：
GSK-5959 (3a) also displays selectivity over the closely related family members, BRPF2 (100-fold) and BRPF3 (>1000-fold).GSK-5959 (3a) exhibits an EC50 = 0.98 μM) in cellular NanoBRET assay.GSK-5959 has no effect on TRIM24 SUMOylation.
产品资料
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