产品
编 号:F511538
产品类型
结构图
CAS No: 9008-97-3
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生物活性:
Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, accumulates in the parenchyma cells of the cotyledons. Phytohemagglutinin is a T-cell activator. Stimulation of human mononuclear leukocytes by Phytohemagglutinin induces the expression of ChAT mRNA, and potentiated ACh synthesis.
体内研究:
Phytohemagglutinin (100 μg; i.p.; daily for 2 days) inhibits A20 tumor growth.Animal Model:CB17-SCID Mice (bearing A20 cells)
Dosage:100 μg
Administration:I.p.; daily for 2 days
Result:Inhibited A20 tumor growth.
体外研究:
Phytohemagglutinin (PHA-M) binds to the membranes of T-cells, stimulates metabolic activity, cell division, and involves inflammatory pathways.