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编 号:F511296
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CAS No: 9005-49-6
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生物活性:
Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. Heparin significantly inhibits exosome-cell interactions.
体外研究:
Heparin (6 天) 可降低 HIV 对 MT-4 细胞的细胞致病性,IC50 为 7.5 μg/mL。Heparin (0.5 U/mL,48 小时) 抑制 SGHPL-4 细胞系中 HGF 诱导的滋养层侵袭。