产品
编 号:F511126
分子式:C12H15ClN2
分子量:222.71
产品类型
结构图
CAS No: 90038-01-0
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生物活性:
Detomidine hydrochloride, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine hydrochloride produces dose-dependent analgesic effects.
体外研究:
Currently, detomidine is only licenced for use in horses. α2-adrenergic agonists produce dose-dependent analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.