产品
编 号:F511072
分子式:C21H24N4O3
分子量:380.44
产品类型
结构图
CAS No: 900305-37-5
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产品详情
生物活性:
PFI-4 (compound 11) is a potent and highly selective BRPF1 Bromodomain (BRPF1B) inhibitor, with an IC50 of 172 nM. PFI-4 can be used to explore the functional mechanisms of the HBO1/BRPF1 complex and to study bone loss and osteolytic malignant bone lesions.
体外研究:
PFI-4 (1.25 μM; 7 or 11 days) inhibits differentiation of human osteoclasts.