产品
编 号:F505798
分子式:C30H31N5O4
分子量:525.6
产品类型
结构图
CAS No: 894783-71-2
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产品详情
生物活性:
BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC50 of 62 nM.
体外研究:
The major metabolic pathway for BIBF 1120 is methyl ester cleavage to BIBF 1202. Subsequently, the free carboxyl group of BIBF 1202 is glucuronidated to 1-O-acylglucuronide.