产品
编 号：F505168
分子式：C25H37NO4
分子量：415.57
分子式：C25H37NO4
分子量：415.57
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 89365-50-4
产品详情
生物活性：
Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
体内研究：
Salmeterol (0.16 mg/kg)、Formoterol (0.32 mg/kg) 联合处理对慢性阻塞性肺疾病 (COPD) 小鼠具有改善作用。Animal Model:Male C57BL/6 mice (6-8 weeks old, body weight: 32-35 g)
Dosage:Salmeterol (0.16 mg/kg) and/or Formoterol (0.32 mg/kg)
Administration:The therapeutic efficacy of co-treatment was investigated in this model over a 56-day-long observation period.
Result:COPD assessment test scores were markedly improved in mice with COPD.
体外研究：
Salmeterol (0.001-25 μM) 抑制人 T 淋巴细胞增殖。
Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
体内研究：
Salmeterol (0.16 mg/kg)、Formoterol (0.32 mg/kg) 联合处理对慢性阻塞性肺疾病 (COPD) 小鼠具有改善作用。Animal Model:Male C57BL/6 mice (6-8 weeks old, body weight: 32-35 g)
Dosage:Salmeterol (0.16 mg/kg) and/or Formoterol (0.32 mg/kg)
Administration:The therapeutic efficacy of co-treatment was investigated in this model over a 56-day-long observation period.
Result:COPD assessment test scores were markedly improved in mice with COPD.
体外研究：
Salmeterol (0.001-25 μM) 抑制人 T 淋巴细胞增殖。
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