产品
编 号：F504356
分子式：C13H17ClN2O
分子量：252.74
分子式：C13H17ClN2O
分子量：252.74
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 89197-00-2
产品详情
生物活性：
Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease.
体内研究：
Efaroxan hydrochloride increases plasma insulin levels in both conscious fed and fasted rats without greatly affecting plasma glucoselevels.Animal Model:Male Sprague-Dawley rats (weight range 250-300g)
Dosage:1 mg/kg, 5 mg/kg
Administration:Oral administration
Result:Produced a significant increase in plasma insulin levels of starved rats 15 and 30 min after treatment.
体外研究：
Efaroxan hydrochloride binds to I1-imidazoline and α2-adrenergic receptors in bovine rostral ventrolateral medulla membranes, with Kis of 0.15 nM and 5.6 nM, respectively
Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease.
体内研究：
Efaroxan hydrochloride increases plasma insulin levels in both conscious fed and fasted rats without greatly affecting plasma glucoselevels.Animal Model:Male Sprague-Dawley rats (weight range 250-300g)
Dosage:1 mg/kg, 5 mg/kg
Administration:Oral administration
Result:Produced a significant increase in plasma insulin levels of starved rats 15 and 30 min after treatment.
体外研究：
Efaroxan hydrochloride binds to I1-imidazoline and α2-adrenergic receptors in bovine rostral ventrolateral medulla membranes, with Kis of 0.15 nM and 5.6 nM, respectively
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