产品
编 号：F504048
分子式：C15H12N2O2
分子量：252.27
分子式：C15H12N2O2
分子量：252.27
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
2mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 891025-25-5
产品详情
生物活性：
BAMB-4 (ITPKA-IN-C14) is a specific and membrane-permeable ITPKA inhibitor. BAMB-4 has high stability and membrane permeability and against the inositol-1,4,5-trisphosphate (InsP3) kinase activity of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA) with an IC50 value of 20 μM. BAMB-4 can be used for the research of metastasis of lung cancer.
体外研究：
BAMB-4 (0.3-40 μM) has ITPKA inhibiton effect with an IC50 value of 37 μM.BAMB-4 (40 μM) inhibits InsP3 kinase activity with an IC50 value of 20 μM.BAMB-4 (100 μM, overnight) has high specificity and the high cellular uptake.BAMP-4 (0, 10, 20 and 40 μM) shows increased Km and decreased V max .BAMP-4 (0-30 μM) is a mixed type inhibitor with respect to ATP and InsP3 and does notonly affect binding of ATP but also binding of InsP3，which affects turnover of two substrate exhibit a higher inhibition specifcity.
BAMB-4 (ITPKA-IN-C14) is a specific and membrane-permeable ITPKA inhibitor. BAMB-4 has high stability and membrane permeability and against the inositol-1,4,5-trisphosphate (InsP3) kinase activity of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA) with an IC50 value of 20 μM. BAMB-4 can be used for the research of metastasis of lung cancer.
体外研究：
BAMB-4 (0.3-40 μM) has ITPKA inhibiton effect with an IC50 value of 37 μM.BAMB-4 (40 μM) inhibits InsP3 kinase activity with an IC50 value of 20 μM.BAMB-4 (100 μM, overnight) has high specificity and the high cellular uptake.BAMP-4 (0, 10, 20 and 40 μM) shows increased Km and decreased V max .BAMP-4 (0-30 μM) is a mixed type inhibitor with respect to ATP and InsP3 and does notonly affect binding of ATP but also binding of InsP3，which affects turnover of two substrate exhibit a higher inhibition specifcity.
产品资料
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